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The most common over-the-counter antihistamine medications, known as first-generation antihistamines, work by blocking histamines.

However, they also cross the blood-brain barrier, interacting with a number of unintended receptor sites. While dangerous in itself, particularly for driving or operating machinery, this sedation also induces an unnatural sleep, interfering with the body’s recovering time, when the brain normally stores memories and retains learning.

Receptor binding data indicate that at a concentration of 2–3 ng/m L (7 nanomolar), desloratadine shows significant interaction with the human histamine H1-receptor.

Seasonal allergic rhinitis: 60 mg orally twice daily or 180 mg once daily.

(Natural Health365) Whether you suffer from seasonal allergies or are susceptible to common year-round allergy triggers, such as certain foods or dust, allergy symptoms can impact your everyday life.

Allergens release histamines that attack your body’s cells, causing the familiar symptoms of runny nose, sneezing and watery eyes.

Please see package insert for additional information and possible updates.

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.




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